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[PubMed: 5469087] 18

For someone weighing this type of treatment against lifestyle changes alone, the honest answer is that these approaches are not competing options

Mechanistically, SLC38A5 mediates the activation of the PI3K/AKT/mTOR signaling pathway by transporting glutamine, which subsequently enhances the SREBP1/SCD-1 signaling pathway, thereby suppressing ferroptosis in osteosarcoma cells